SCHEMBL3366835

SCHEMBL3366835

Oc1ccc(-c2cccc3c2Cc2ccccc2-3)cc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.47
HSD17B2 P37059 1/20 0.47
BACE1 P56817 2/20 0.44
PNMT P11086 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
BCL2L1 Q07817 1/20 0.43
HSD17B10 Q99714 1/20 0.43
APP P05067 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PRCP P42785 1/20 0.39
PELI1 Q96FA3 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
KDR P35968 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
ALOX5 P09917 1/20 0.37
ANPEP P15144 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28628895 0.89 ALOX5 (0.46) HSD17B1HSD17B2BACE1PNMTALDH1A1
SCHEMBL4631140 0.87 BACE1 (0.41) HSD17B1HSD17B2BACE1PNMTALDH1A1
SCHEMBL29126249 0.86 KDM4E (0.41) HSD17B1HSD17B2BACE1PNMTALDH1A1
SCHEMBL21295458 0.86 APP (0.58) PNMTAPPNPC1RAB9AADORA2A
SCHEMBL28024155 0.85 PNMT (0.50) HSD17B1HSD17B2BACE1PNMTAPP
SCHEMBL29126292 0.85 HTR1A (0.46) PNMTALDH1A1MAOBHTR7
SCHEMBL27819054 0.84 PNMT (0.46) BACE1PNMTALDH1A1HPGDBCL2L1
SCHEMBL21295456 0.84 PNMT (0.43) BACE1PNMTALDH1A1HPGDBCL2L1
SCHEMBL28928665 0.84 PNMT (0.50) PNMTNPC1RAB9APRCPKDR
SCHEMBL70992 0.83 PNMT (0.53) PNMTNPC1RAB9APRCPKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736073-A Synthesis method of 9, 9-bis (3-phenyl-4-hydroxyphenyl) fluorene 中唯炼焦技术国家工程研究中心有限责任公司 2024-03-22 CN claimed
CN-109195936-B Method for producing alcohols having fluorene skeleton 田冈化学工业株式会社 2022-02-11 CN claimed
CN-112888579-B Rubber-like composition and method for producing same 大阪瓦斯株式会社 2024-07-09 CN disclosed
CN-118251442-A Process for producing polyether nitrile 本州化学工业株式会社 2024-06-25 CN disclosed
CN-118251441-A Process for producing polyether nitrile 本州化学工业株式会社 2024-06-25 CN disclosed
CN-118251460-A Polycarbonate resin composition and optical lens using the same 三菱瓦斯化学株式会社 2024-06-25 CN disclosed
CN-118234780-A Process for producing polyether nitrile 本州化学工业株式会社 2024-06-21 CN disclosed
US-20240199924-A1 LAMINATE, RELEASE AGENT COMPOSITION, AND METHOD FOR MANUFACTURING PROCESSED SEMICONDUCTOR SUBSTRATE NISSAN CHEMICAL CORPORATION (JP) 2024-06-20 US disclosed
CN-118176235-A Thermoplastic resin and optical member 帝人株式会社 2024-06-11 CN disclosed
CN-113474685-B optical lens 帝人株式会社 2024-05-28 CN disclosed
CN-118043298-A (Hetero) aryl-substituted bisphenol compound and thermoplastic resin 罗伊特化学仪器制造公司 2024-05-14 CN disclosed
CN-1802573-A Optical films comprising one or more polyarylates obtained from specific phenolic molecules FERRANIA TECHNOLOGIES SPA (IT) 2006-07-12 CN disclosed
CN-1737697-A Transfer material carrying member, intermediate transfer member, and image forming apparatus using the same CANON KK (JP) 2006-02-22 CN disclosed
CN-1207322-C Method for producing polycarbonate resin raw material and polycarbonate resin IDEMITSU PETROCHEMICAL CO (JP) 2005-06-22 CN disclosed
CN-1622965-A Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO (JP) 2005-06-01 CN disclosed
EP-1138714-B1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL CO (JP) 2005-02-23 EP disclosed
CN-1364176-A Processes for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO (JP) 2002-08-14 CN disclosed
EP-1138714-A2 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-10-04 EP disclosed
WO-1996029366-A1 BLENDS OF DIARYL FLUORENE CARBONATE POLYMERS WITH BISPHENOL A CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO disclosed
US-5486577-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1996-01-23 US disclosed