SCHEMBL4631356

SCHEMBL4631356

Cc1ccc2c(c1)C(C)(c1cc(C)c(O)c(C)c1)CC(C)(C)O2

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.34
ACHE P22303 1/20 0.34
CNR2 P34972 1/20 0.34
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX5 P09917 2/20 0.31
PTGS1 P23219 2/20 0.31
PTGS2 P35354 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
G6PD P11413 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP26A1 O43174 1/20 0.30
CYP26B1 Q9NR63 1/20 0.30
CCR2 P41597 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21451227 0.84 MAPT (0.38) AKR1B1ACHECNR2MAPTL3MBTL1
SCHEMBL7740730 0.84 LMNA (0.35) AKR1B1ACHECNR2MAPTL3MBTL1
SCHEMBL6838753 0.78 FTO (0.41) ACHECNR2MAPTL3MBTL1ALDH1A1
SCHEMBL6906553 0.74 BACE1 (0.43) AKR1B1MAPTALDH1A1GAA
SCHEMBL7738248 0.71 MEN1 (0.48) AKR1B1CNR2MAPTL3MBTL1ALDH1A1
SCHEMBL6910911 0.71 AKR1B1 (0.37) AKR1B1CNR2MAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL6560825 0.70 BACE1 (0.38) AKR1B1
SCHEMBL4631373 0.69 FTO (0.44) AKR1B1CNR2MAPTL3MBTL1ALDH1A1
SCHEMBL10753224 0.69 AKR1B1 (0.50) AKR1B1CNR2MAPTALDH1A1
SCHEMBL27454580 0.67 ALOX5 (0.34) ACHECNR2MAPTL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP claimed
EP-1472302-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2004-11-03 EP claimed
WO-2002046272-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2002-06-13 WO claimed
CN-100445316-C Recycling process for polycondensation resins GEN ELECTRIC (US) 2008-12-24 CN disclosed
EP-1156071-B2 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2008-08-06 EP disclosed
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP disclosed
US-7112645-B2 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate GENERAL ELECTRIC COMPANY (US) 2006-09-26 US disclosed
EP-1141082-B1 METHOD OF MANUFACTURING POLYCARBONATES GEN ELECTRIC (US) 2005-11-30 EP disclosed
WO-2005092951-A1 A POLYCARBONATE COMPOSITION AND METHOD OF MAKING THEREOF GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2005-10-06 WO disclosed
CN-1221590-C Optical polycarbonate and application thereof GEN ELECTRIC (US) 2005-10-05 CN disclosed
US-20050209434-A1 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate CITIBANK, N.A., AS COLLATERAL AGENT 2005-09-22 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
US-4788275-A DUCTILITY, IMPACT AND TENSILE STRENGTH, HEAT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1988-11-29 US disclosed
EP-0272424-A2 Copolyestercarbonate composition GENERAL ELECTRIC COMPANY (US) 1988-06-29 EP disclosed