SCHEMBL4631373

SCHEMBL4631373

Cc1ccc2c(c1)C(C)(C)CC(C)(c1cc(C)cc(C)c1O)O2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.44
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AKR1B1 P15121 1/20 0.32
TRPA1 O75762 2/20 0.32
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32
TRPV1 Q8NER1 2/20 0.32
TRPV3 Q8NET8 2/20 0.32
TRPV4 Q9HBA0 2/20 0.32
TRPV2 Q9Y5S1 2/20 0.32
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
CYP26A1 O43174 1/20 0.30
CYP26B1 Q9NR63 1/20 0.30
CYP1A1 P04798 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911113 0.87 FTO (0.39) FTOALDH1A1L3MBTL1TRPA1CNR1
SCHEMBL6838753 0.86 FTO (0.41) FTOALDH1A1L3MBTL1TDP1CNR2
SCHEMBL7525551 0.84 FTO (0.54) FTOALDH1A1L3MBTL1TP53TDP1
SCHEMBL7520930 0.83 FTO (0.52) FTOTP53TDP1AKR1B1TRPA1
SCHEMBL12251392 0.75 FTO (0.42) FTOALDH1A1TRPA1CNR1CNR2
SCHEMBL9008421 0.74 FTO (0.52) FTOALDH1A1L3MBTL1TP53TDP1
SCHEMBL7522360 0.74 KDM4E (0.34) FTOALDH1A1TP53TDP1AKR1B1
SCHEMBL4665594 0.72 FTO (0.54) FTOALDH1A1TP53TDP1TRPA1
SCHEMBL29908705 0.72 FTO (0.54) FTOALDH1A1TP53TDP1TRPA1
SCHEMBL7522231 0.72 FTO (0.53) FTOTP53TDP1TRPA1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP claimed
EP-1472302-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2004-11-03 EP claimed
WO-2002046272-A2 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2002-06-13 WO claimed
CN-100445316-C Recycling process for polycondensation resins GEN ELECTRIC (US) 2008-12-24 CN disclosed
EP-1156071-B2 A method for manufacturing polycarbonate GEN ELECTRIC (US) 2008-08-06 EP disclosed
EP-1472302-B1 POLYCARBONATE RESIN COMPOSITION FOR OPTICAL APPLICATIONS AND METHODS FOR MANUFACTURE THEREOF GEN ELECTRIC (US) 2008-05-21 EP disclosed
EP-1151027-B1 OPTICAL DISC COMPRISING POLYCARBONATE WITH REDUCED LEVELS OF FRIES GEN ELECTRIC (US) 2008-05-14 EP disclosed
US-7112645-B2 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate GENERAL ELECTRIC COMPANY (US) 2006-09-26 US disclosed
EP-1141082-B1 METHOD OF MANUFACTURING POLYCARBONATES GEN ELECTRIC (US) 2005-11-30 EP disclosed
WO-2005092951-A1 A POLYCARBONATE COMPOSITION AND METHOD OF MAKING THEREOF GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2005-10-06 WO disclosed
CN-1221590-C Optical polycarbonate and application thereof GEN ELECTRIC (US) 2005-10-05 CN disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
US-5403878-A With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability CITIBANK, N.A., AS COLLATERAL AGENT 1995-04-04 US disclosed
US-5389713-A Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound GE PLASTICS JAPAN (JP) 1995-02-14 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed