Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22641245 | 0.83 | PTGS2 (0.48) | PTGS2TDP1L3MBTL1PDE4APDE4B | |
| SCHEMBL4881459 | 0.79 | CRHR1 (0.33) | PTGS2 | |
| SCHEMBL6603590 | 0.77 | MAPT (0.38) | NPC1RAB9A | |
| SCHEMBL2853131 | 0.75 | ALDH1A1 (0.32) | TDP1 | |
| SCHEMBL8272903 | 0.74 | ALDH1A1 (0.44) | TDP1L3MBTL1POLB | |
| SCHEMBL22978573 | 0.73 | ALDH1A1 (0.37) | TDP1PDE4APDE4DNPC1POLB | |
| SCHEMBL6607673 | 0.73 | CRHR1 (0.35) | — | |
| SCHEMBL2597202 | 0.72 | NOS3 (0.35) | — | |
| SCHEMBL2851798 | 0.72 | PDE4A (0.36) | L3MBTL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2853192 | 0.71 | XPO1 (0.35) | L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924558-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007032016-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | disclosed |