Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891251 | 0.97 | — | — | |
| Water SCHEMBL2156886 | 0.95 | — | — | |
| SCHEMBL9862231 | 0.94 | CA4 (0.31) | — | |
| Water SCHEMBL10536890 | 0.92 | — | — | |
| Potassium Ion SCHEMBL1247405 | 0.87 | CPT2 (0.32) | — | |
| SCHEMBL8102542 | 0.86 | CA2 (0.31) | — | |
| SCHEMBL284822 | 0.85 | TDP1 (0.34) | — | |
| Water SCHEMBL9444829 | 0.84 | CPT2 (0.30) | — | |
| SCHEMBL11131358 | 0.83 | CPT2 (0.32) | — | |
| Silver SCHEMBL3355297 | 0.83 | CPT2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696643-B1 | Apparatus for inhibiting glycolysis in blood samples | BECTON DICKINSON CO (US) | 2004-05-19 | — | — | EP | claimed |
| EP-1923449-A1 | Colloidal suspensions of nanoscale particles | Koninklijke Philips Electronics N.V. (NL) | 2008-05-21 | — | — | EP | disclosed |
| US-20030143758-A1 | Insoluble carrier particle nephelometric immunoassay reagent | SRL, INC. (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1298438-A1 | INSOLUBLE CARRIER PARTICLE NEPHELOMETRIC IMMUNOASSAY REAGENT | KYOWA MEDEX CO., LTD. (JP) | 2003-04-02 | — | — | EP | disclosed |