SCHEMBL4632504

SCHEMBL4632504

C=CC(O)Nc1ccc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 3/20 0.46
HSD17B10 Q99714 3/20 0.46
HPGD P15428 3/20 0.46
CYP1A2 P05177 3/20 0.46
CYP2C19 P33261 2/20 0.46
HIF1A Q16665 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
MAPT P10636 4/20 0.43
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
GAA P10253 1/20 0.41
TEAD4 Q15561 1/20 0.41
KDM4E B2RXH2 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646260 0.78 TDP1 (0.44) ALDH1A1CYP3A4HSD17B10CYP1A2HIF1A
SCHEMBL29078124 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4HSD17B10HPGDCYP1A2
SCHEMBL29078168 0.77 ALDH1A1 (0.46) ALDH1A1CYP3A4HSD17B10HPGDCYP1A2
SCHEMBL10401390 0.77 UGT2B7 (0.52) ALDH1A1CYP3A4HSD17B10HPGDCYP1A2
SCHEMBL11422092 0.74 POLB (0.42) ALDH1A1MAPTRAB9ANPC1MEN1
SCHEMBL14188196 0.74 CYP3A4 (0.50) ALDH1A1CYP3A4HSD17B10HPGDCYP1A2
SCHEMBL22225161 0.73 MMP2 (0.31) CA1
SCHEMBL15566058 0.72 ALDH1A1 (0.52) ALDH1A1CYP3A4HSD17B10HPGDCYP1A2
SCHEMBL9359370 0.72 TDP1 (0.54) ALDH1A1CYP3A4HSD17B10HPGDCYP1A2
SCHEMBL24004109 0.72 RAB9A (0.53) ALDH1A1CYP3A4HSD17B10HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed