SCHEMBL22225161

SCHEMBL22225161

Bc1cccc(NC(O)C=C)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA14 Q9ULX7 2/20 0.30
CA9 Q16790 1/20 0.30
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646260 0.77 TDP1 (0.44) CA12CA9TGM2
SCHEMBL4632504 0.73 ALDH1A1 (0.46) CA1
SCHEMBL18893123 0.71 TDP1 (0.54) MMP2CA12CA1CA14CA9
SCHEMBL11422092 0.69 POLB (0.42)
SCHEMBL13458515 0.68 MMP2 (0.65) MMP2CA12CA1CA14CA9
SCHEMBL26483965 0.68 TGM2 (0.65) TGM2
SCHEMBL6255896 0.66 MAPT (0.39) CA12CA1CA14CA9
SCHEMBL21787328 0.66 TDP1 (0.46) CA1CA9
SCHEMBL3952756 0.66 CA1 (0.46) CA12CA1TGM2
SCHEMBL6533910 0.66 NPSR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787930-B2 Flow cell including a heteropolymer ILLUMINA INC. (US) 2023-10-17 US disclosed
US-20200224020-A1 FLOW CELL INCLUDING A HETEROPOLYMER ILLUMINA CAMBRIDGE LIMITED (GB) 2020-07-16 US disclosed