Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276273 | 1.00 | SLC6A2 (0.39) | SLC6A2SLC6A3SLC6A4TP53KMT2A | |
| SCHEMBL4633331 | 0.88 | ENPP2 (0.37) | TP53KMT2ACYP3A4LMNATSHR | |
| SCHEMBL4268901 | 0.88 | ENPP2 (0.37) | TP53KMT2ACYP3A4LMNATSHR | |
| SCHEMBL7025599 | 0.70 | CHRM3 (0.39) | SLC6A2SLC6A3KMT2ACYP3A4CHRM2 | |
| SCHEMBL7795340 | 0.69 | SMN1; SMN2 (0.38) | TP53KMT2AADRA2AKCNH2LMNA | |
| SCHEMBL20856173 | 0.69 | SMN1; SMN2 (0.38) | TP53KMT2AADRA2AKCNH2LMNA | |
| SCHEMBL7023153 | 0.68 | PTGIR (0.36) | KMT2ACHRM2CHRM1SMN1; SMN2MEN1 | |
| SCHEMBL7025600 | 0.66 | CHRM2 (0.38) | SLC6A2SLC6A3KMT2ACHRM2HTR1A | |
| SCHEMBL4268095 | 0.65 | L3MBTL1 (0.36) | KMT2AL3MBTL1SMN1; SMN2MEN1KDM4E | |
| SCHEMBL20162538 | 0.65 | ALDH1A1 (0.35) | TP53KMT2ACHRM2CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |
| EP-1928475-A2 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-SUBSTITUTED PRONUCLEOTIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007020193-A2 | ANTIVIRAL PHOSPHORAMIDATES OF 4 ' -SUBSTITUTED PRONUCLEOTIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-22 | — | — | WO | disclosed |