Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364205 | 0.81 | VCAM1 (0.52) | HCAR3ALDH1A1TPMTMEN1KMT2A | |
| SCHEMBL10541690 | 0.80 | HCAR3 (0.68) | HCAR3CASP6TSHRALDH1A1TPMT | |
| SCHEMBL503451 | 0.79 | TSHR (0.65) | HCAR3CASP6TSHRALDH1A1TPMT | |
| SCHEMBL7826111 | 0.78 | HCAR3 (0.68) | HCAR3CASP6TSHRALDH1A1TPMT | |
| SCHEMBL2772069 | 0.77 | HCAR3 (1.00) | HCAR3CASP6TSHRALDH1A1HPGD | |
| SCHEMBL10539731 | 0.77 | HPGD (0.44) | HCAR3CASP6TSHRALDH1A1TPMT | |
| SCHEMBL8841185 | 0.76 | CASP6 (0.62) | HCAR3CASP6TSHRALDH1A1TPMT | |
| SCHEMBL10945219 | 0.76 | CASP6 (0.62) | HCAR3CASP6TSHRALDH1A1TPMT | |
| SCHEMBL503443 | 0.76 | CASP6 (0.62) | HCAR3CASP6TSHRALDH1A1TPMT | |
| SCHEMBL28401769 | 0.76 | CASP6 (0.62) | HCAR3CASP6TSHRALDH1A1TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926714-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | Nycomed GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2008017466-A1 | PHARMACEUTICALLY ACTIVE TETRAHYDROISOQUINOLINE-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-02-14 | — | — | WO | disclosed |
| WO-2007023135-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2007-03-01 | — | — | WO | disclosed |
| EP-1350102-A2 | DETECTION OF ANALYTES | Sensors for Medicine and Science, Inc. (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | THE UNIVERSITY OF MANCHESTER (GB) | 2003-06-12 | — | — | US | disclosed |
| EP-1242360-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2002-09-25 | — | — | EP | disclosed |
| US-20020119581-A1 | Detection of analytes | SENSORS FOR MEDICINE AND SCIENCE, INC. | 2002-08-29 | — | — | US | disclosed |
| US-20020094586-A1 | Detection of analytes | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2002-07-18 | — | — | US | disclosed |
| WO-2002054067-A2 | DETECTION OF ANALYTES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2002-07-11 | — | — | WO | disclosed |
| WO-2001046121-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2001-06-28 | — | — | WO | disclosed |
| US-5401604-A | Reaction product of polyepoxide, aromatic acid with phenolic hydroxy group, aromatic acid, quinone diazide with sulfonyl group, photoresists | NIPPON PAINT CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | MDM4, PHAX, DIMT1 | HCAR3 2975/4885CASP6 3402/4885TSHR 2358/4885 |
| US-20020094586-A1 | Detection of analytes | AKR7A2, DDX6, ANXA6 | HCAR3 3157/4885CASP6 334/4885TSHR 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.