Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 15/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 15/20 | 0.43 |
| ▸ | PARP1 | P09874 | 12/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438489 | 0.83 | TNKS (0.48) | TNKSTNKS2PARP1 | |
| SCHEMBL16462782 | 0.79 | WNT1 (0.47) | TNKSTNKS2PARP1 | |
| SCHEMBL408283 | 0.79 | MEN1 (0.51) | TNKSTNKS2PARP1 | |
| Hydrochloric Acid SCHEMBL440170 | 0.78 | MEN1 (0.54) | TNKSTNKS2PARP1 | |
| SCHEMBL408317 | 0.76 | GPR119 (0.57) | TNKSTNKS2PARP1 | |
| SCHEMBL18824281 | 0.74 | TNKS (0.57) | TNKSTNKS2PARP1 | |
| SCHEMBL18824353 | 0.72 | TNKS (0.60) | TNKSTNKS2PARP1 | |
| SCHEMBL462944 | 0.71 | MGLL (0.60) | — | |
| SCHEMBL13657578 | 0.70 | MGLL (0.71) | — | |
| SCHEMBL872178 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | TNKS 4718/4885TNKS2 4435/4885PARP1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.