Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632947 | 0.91 | KMT2A (0.57) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4632948 | 0.91 | KMT2A (0.56) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4632923 | 0.89 | KMT2A (0.47) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4633564 | 0.89 | LMNA (0.49) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4667233 | 0.85 | ALDH1A1 (0.46) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4634476 | 0.85 | RAB9A (0.47) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4635042 | 0.85 | MAPT (0.50) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4633553 | 0.85 | ALDH1A1 (0.60) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4633878 | 0.84 | CXCR2 (0.46) | KMT2AALDH1A1NOD2LMNAMAPT | |
| SCHEMBL4633530 | 0.82 | L3MBTL1 (0.60) | KMT2AALDH1A1NOD2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |