Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632947 | 0.87 | KMT2A (0.57) | ALDH1A1KMT2ANOD2LMNAHPGD | |
| SCHEMBL4632948 | 0.87 | KMT2A (0.56) | ALDH1A1KMT2ANOD2LMNANPC1 | |
| SCHEMBL4633861 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KMT2ANOD2LMNANPC1 | |
| SCHEMBL1385589 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KMT2ANOD2LMNAHPGD | |
| SCHEMBL4633907 | 0.85 | KMT2A (0.47) | ALDH1A1KMT2ANOD2LMNANPC1 | |
| SCHEMBL4633564 | 0.85 | LMNA (0.49) | ALDH1A1KMT2ANOD2LMNAHPGD | |
| SCHEMBL4632923 | 0.85 | KMT2A (0.47) | ALDH1A1KMT2ANOD2LMNAHPGD | |
| SCHEMBL4667132 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2ANOD2LMNASENP5 | |
| SCHEMBL4634476 | 0.83 | RAB9A (0.47) | ALDH1A1KMT2ANOD2LMNANPC1 | |
| SCHEMBL4634440 | 0.79 | SENP5 (0.52) | ALDH1A1KMT2ALMNAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685121-B1 | ANTIDIABETIC COMPOUNDS COMPRISING BENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-06-11 | — | — | EP | claimed |