Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.39 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870041 | 0.84 | SLC6A9 (0.50) | ALDH1A1IRAK4XDHSLC6A9 | |
| SCHEMBL4037723 | 0.82 | HNF4A (0.56) | ALDH1A1IRAK4SLC6A9 | |
| SCHEMBL711082 | 0.78 | ALDH1A1 (0.73) | ALDH1A1IRAK4CFDKMT2A | |
| SCHEMBL17908023 | 0.77 | CSNK2A1 (0.52) | ALDH1A1IRAK4XDHCFDKMT2A | |
| SCHEMBL4017686 | 0.76 | ALDH1A1 (0.50) | ALDH1A1IRAK4XDHCFDKMT2A | |
| SCHEMBL17040592 | 0.76 | TSHR (0.53) | ALDH1A1IRAK4RORCKMO | |
| SCHEMBL28091356 | 0.76 | ALDH1A1 (0.50) | ALDH1A1IRAK4XDHCFDKMT2A | |
| SCHEMBL4317654 | 0.76 | ALDH1A1 (0.50) | ALDH1A1IRAK4XDHCFDKMT2A | |
| SCHEMBL727897 | 0.76 | ALDH1A1 (0.53) | ALDH1A1IRAK4XDHCFDKMT2A | |
| SCHEMBL4019340 | 0.76 | FFAR1 (0.51) | ALDH1A1IRAK4SLC6A9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221195-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2008-09-11 | — | — | US | disclosed |
| WO-2008071453-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-06-19 | — | — | WO | disclosed |
| EP-1932831-A1 | 1,2-Diarylacetylene Derivatives of Acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221195-A1 | 1,2-DIARYLACETYLENE DERIVATIVES OF ACYLTRYPTOPHANOLS | FSHR, GNRHR, TPH1 | ALDH1A1 2416/4885IRAK4 4568/4885XDH 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.