SCHEMBL4634282

SCHEMBL4634282

[S]n1nnc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 9/20 0.56
MAPT P10636 2/20 0.56
POLB P06746 1/20 0.56
MAPK1 P28482 1/20 0.56
ATM Q13315 1/20 0.56
KEAP1 Q14145 1/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
THPO P40225 1/20 0.56
CYP4Z1 Q86W10 1/20 0.56
DGAT1 O75907 1/20 0.50
GRM2 Q14416 1/20 0.47
RAB9A P51151 3/20 0.46
KCNMA1 Q12791 1/20 0.46
NPC1 O15118 2/20 0.44
MGAM O43451 1/20 0.44
F2 P00734 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11959496 0.76 SLC9A1 (0.56) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL3072391 0.75 SLC9A1 (0.60) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL13602385 0.71 SLC9A1 (0.56) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL14410635 0.71 SLC9A1 (0.56) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL247973 0.71 SLC9A1 (0.56) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL422528 0.71 POLB (0.61) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL18372356 0.71 SLC9A1 (0.56) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL3672275 0.71 POLB (1.00) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL15548600 0.71 SLC9A1 (0.56) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL1012471 0.71 POLB (1.00) SLC9A1MAPTPOLBMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
US-20050208425-A1 Imide compound and optical recording media made by using the same YAMAMOTO CHEMICALS, INC. (JP) 2005-09-22 US disclosed
EP-1445115-A1 IMIDE COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050208425-A1 Imide compound and optical recording media made by using the same CRY1, MTNR1A, TRPA1 SLC9A1 736/4885MAPT 2420/4885POLB 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.