SCHEMBL46350

SCHEMBL46350

CON1CCC(N)(N(C)C(=O)Cc2cc(Br)c(C)cc2C)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL46062 0.91 KDM4E (0.32) TSHR
SCHEMBL46128 0.91 L3MBTL1 (0.34)
SCHEMBL46051 0.88 ERBB2 (0.30)
SCHEMBL46374 0.86 OPRM1 (0.33) TSHRSMN1; SMN2
SCHEMBL12071754 0.84 SIGMAR1 (0.33) TSHRSMN1; SMN2
SCHEMBL15032126 0.84 RXFP1 (0.33) TSHRSMN1; SMN2
SCHEMBL46336 0.83 MAPT (0.35) SMN1; SMN2
SCHEMBL46058 0.83 KDM4E (0.34) SMN1; SMN2
SCHEMBL12071745 0.82 EZH2 (0.32)
SCHEMBL12071750 0.81 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011151249-A2 METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA SYNGENTA PARTICIPATIONS AG (CH) 2011-12-08 WO disclosed
WO-2010066780-A1 SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-06-17 WO disclosed