Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948375 | 0.85 | CNR1 (0.41) | CYP2C19TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL9974573 | 0.78 | KEAP1 (0.56) | CYP2C19ALDH1A1KEAP1NFE2L2CNR2 | |
| SCHEMBL145821 | 0.77 | CYP2C19 (0.50) | CYP2C19TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL33921 | 0.73 | CYP2C19 (0.47) | CYP2C19TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL17689350 | 0.71 | ALDH1A1 (0.46) | CYP2C19TSHRALDH1A1CNR2TDP1 | |
| SCHEMBL3348811 | 0.71 | KEAP1 (0.49) | CYP2C19TSHRKEAP1NFE2L2CNR2 | |
| SCHEMBL2805280 | 0.71 | KMT2A (0.50) | CYP2C19TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL7108072 | 0.70 | ALDH1A1 (0.46) | CYP2C19TSHRALDH1A1KEAP1NFE2L2 | |
| SCHEMBL516400 | 0.70 | CYP2C19 (0.48) | CYP2C19TSHRALDH1A1CNR2ACHE | |
| Bicarbonate SCHEMBL11138673 | 0.70 | CNR2 (0.56) | CYP2C19TSHRALDH1A1CNR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512298-B2 | Specific mixtures of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS DEUTSCHLAND GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-9512298-B2 | Specific mixtures of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS DEUTSCHLAND GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-9512298-B2 | Specific mixtures of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS DEUTSCHLAND GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20130116395-A1 | Specific mixtrues of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS Deutschland (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130116395-A1 | Specific mixtrues of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS Deutschland (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130116395-A1 | Specific mixtrues of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS Deutschland (DE) | 2013-05-09 | — | — | US | disclosed |
| EP-1650184-B1 | Mixtures of N,N-Bis-(2-hydroxyalkyl)-4-toluidin, their preparation and use | SALTIGO GMBH (DE) | 2008-01-23 | — | — | EP | disclosed |
| EP-1650184-B1 | Mixtures of N,N-Bis-(2-hydroxyalkyl)-4-toluidin, their preparation and use | SALTIGO GMBH (DE) | 2008-01-23 | — | — | EP | disclosed |
| EP-1650184-A1 | Mixtures of N,N-Bis-(2-hydroxyalkyl)-4-toluidin, their preparation and use | Lanxess Deutschland GmbH (DE) | 2006-04-26 | — | — | EP | disclosed |
| EP-1650184-A1 | Mixtures of N,N-Bis-(2-hydroxyalkyl)-4-toluidin, their preparation and use | Lanxess Deutschland GmbH (DE) | 2006-04-26 | — | — | EP | disclosed |
| EP-1650184-A1 | Mixtures of N,N-Bis-(2-hydroxyalkyl)-4-toluidin, their preparation and use | Lanxess Deutschland GmbH (DE) | 2006-04-26 | — | — | EP | disclosed |
| US-20060052555-A1 | Specific mixtures of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS DEUTSCHLAND GMBH | 2006-03-09 | — | — | US | disclosed |
| US-20060052555-A1 | Specific mixtures of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS DEUTSCHLAND GMBH | 2006-03-09 | — | — | US | disclosed |
| US-20060052555-A1 | Specific mixtures of N,N-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS DEUTSCHLAND GMBH | 2006-03-09 | — | — | US | disclosed |
| CN-1743364-A | Specific mixtures of n,n-bis(2-hydroxyalkyl)-4-toluidine derivatives, their preparation and a method of using such specific mixtures | LANXESS DEUTSCHLAND GMBH (DE) | 2006-03-08 | — | — | CN | disclosed |