Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162507 | 1.00 | PPARG (0.38) | PPARGPPARASLC6A3MEN1CYP2D6 | |
| SCHEMBL20162498 | 0.88 | POLB (0.42) | PPARGPPARAALDH1A1MAPTHPGD | |
| SCHEMBL472178 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4EELANE | |
| SCHEMBL20162506 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4EELANE | |
| SCHEMBL645087 | 0.84 | RAB9A (0.41) | PPARGPPARAMEN1KMT2AALDH1A1 | |
| SCHEMBL29794309 | 0.80 | POLB (0.43) | PPARGPPARAALDH1A1MAPTHPGD | |
| SCHEMBL29371149 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDKDM4EELANE | |
| SCHEMBL10004685 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDKDM4EELANE | |
| SCHEMBL472191 | 0.77 | ALDH1A1 (0.38) | KMT2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL6555636 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4EELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |
| EP-1928475-A2 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-SUBSTITUTED PRONUCLEOTIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007020193-A2 | ANTIVIRAL PHOSPHORAMIDATES OF 4 ' -SUBSTITUTED PRONUCLEOTIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-22 | — | — | WO | disclosed |