Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472178 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL20162506 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL29794309 | 0.92 | POLB (0.43) | POLBRXFP1NPC1RAB9ATP53 | |
| SCHEMBL645087 | 0.89 | RAB9A (0.41) | POLBNPC1RAB9AALDH1A1PPARG | |
| SCHEMBL4635211 | 0.88 | PPARG (0.38) | POLBALDH1A1PPARGPPARAMAPT | |
| SCHEMBL20162507 | 0.88 | PPARG (0.38) | POLBALDH1A1PPARGPPARAMAPT | |
| SCHEMBL29371149 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL6555636 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7795340 | 0.81 | SMN1; SMN2 (0.38) | POLBNPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL20856173 | 0.81 | SMN1; SMN2 (0.38) | POLBNPC1RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |