Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.76 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | TACR2 | P21452 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305662 | 0.94 | SIGMAR1 (0.73) | SIGMAR1TMEM97MEN1KMT2AESR1 | |
| SCHEMBL14178223 | 0.89 | MEN1 (0.74) | SIGMAR1TMEM97MEN1KMT2AKDM4E | |
| SCHEMBL274906 | 0.86 | TMEM97 (1.00) | SIGMAR1TMEM97ESR1ADRA2ASLC6A2 | |
| SCHEMBL11539730 | 0.84 | TMEM97 (0.95) | SIGMAR1TMEM97ESR1ADRA2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL5115776 | 0.84 | TMEM97 (0.95) | SIGMAR1TMEM97KMT2AESR1SLC6A2 | |
| Bromide SCHEMBL6337077 | 0.84 | TMEM97 (0.95) | SIGMAR1TMEM97ESR1ADRA2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL27960798 | 0.83 | TMEM97 (0.91) | SIGMAR1TMEM97KMT2AESR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL28659483 | 0.83 | TMEM97 (0.91) | SIGMAR1TMEM97ESR1ADRA2ASLC6A2 | |
| SCHEMBL7031436 | 0.80 | MEN1 (0.63) | SIGMAR1TMEM97MEN1KMT2AL3MBTL1 | |
| SCHEMBL11486199 | 0.79 | ESR1 (0.57) | SIGMAR1TMEM97ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114058655-A | Method for synthesizing (R) -acetamidophenylpropanol by enzyme-chemical one-pot method | 青岛科技大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-114058655-A | Method for synthesizing (R) -acetamidophenylpropanol by enzyme-chemical one-pot method | 青岛科技大学 | 2022-02-18 | — | — | CN | disclosed |
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-1879562-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | Imperial Innovations Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006097744-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | IMPERIAL INNOVATIONS LIMITED (GB) | 2006-09-21 | — | — | WO | disclosed |
| CN-1082042-C | Method for synthesizing lecdopamine | CHENGDU ORGANIC CHEM INST (CN) | 2002-04-03 | — | — | CN | disclosed |
| CN-1073983-C | Method for synthesis of beta-adrenomimetic excitant type fodder additive | CHENGDU ORGANIC CHEM INST (CN) | 2001-10-31 | — | — | CN | disclosed |
| CN-1174830-A | Method for synthesizing lecdopamine | CHENGDU ORGANIC CHEM INST (CN) | 1998-03-04 | — | — | CN | disclosed |
| CN-1116620-A | Method for synthesis of beta-adrenomimetic excitant type fodder additive | CHENGDU ORGANIC CHEM INST (CN) | 1996-02-14 | — | — | CN | disclosed |
| EP-0117647-A1 | Improvements in or relating to phenethanolamines | ELI LILLY AND COMPANY (US) | 1984-09-05 | — | — | EP | disclosed |
| EP-0007205-A1 | Optically active phenethanolamines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
| EP-0007204-A1 | Phenethanolamines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221702-A1 | COMPOUNDS | NCEH1, NME2, HRH3 | SIGMAR1 415/4885TMEM97 1016/4885MEN1 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.