Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757647 | 0.77 | CES2 (0.37) | TSHRSMN1; SMN2 | |
| SCHEMBL4617380 | 0.75 | — | — | |
| SCHEMBL8846928 | 0.68 | THRB (0.34) | TSHRSMN1; SMN2 | |
| SCHEMBL2771873 | 0.67 | — | — | |
| SCHEMBL6435692 | 0.67 | TSHR (0.35) | TSHRSMN1; SMN2 | |
| SCHEMBL7652146 | 0.67 | THRB (0.38) | — | |
| SCHEMBL7652406 | 0.67 | THRB (0.38) | — | |
| SCHEMBL7650483 | 0.67 | THRB (0.38) | — | |
| SCHEMBL4636359 | 0.64 | PKM (0.34) | SMN1; SMN2 | |
| SCHEMBL14322621 | 0.64 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940797-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Array Biopharma, Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007024612-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | ARRAY BIOPHARMA INC. (US) | 2007-03-01 | — | — | WO | disclosed |