Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439231 | 0.87 | MTNR1A (0.42) | MTNR1AMTNR1BTNKSPARP2ENPP2 | |
| SCHEMBL407315 | 0.87 | MTNR1A (0.42) | MTNR1AMTNR1BTNKSPARP2ENPP2 | |
| Hydrochloric Acid SCHEMBL440114 | 0.86 | MTNR1A (0.41) | MTNR1AMTNR1BTNKSPARP2ENPP2 | |
| Hydrochloric Acid SCHEMBL440113 | 0.86 | MTNR1A (0.41) | MTNR1AMTNR1BTNKSPARP2ENPP2 | |
| SCHEMBL443224 | 0.83 | KMT2A (0.43) | MTNR1AMTNR1BTNKSPARP2KMT2A | |
| SCHEMBL443223 | 0.83 | KMT2A (0.43) | MTNR1AMTNR1BTNKSPARP2KMT2A | |
| SCHEMBL408780 | 0.76 | ENPP2 (0.35) | ENPP2KMT2AMEN1LMNACCR5 | |
| SCHEMBL407984 | 0.76 | ENPP2 (0.35) | ENPP2KMT2AMEN1LMNACCR5 | |
| SCHEMBL407345 | 0.76 | PKM (0.37) | ENPP2KMT2AMEN1SMN1; SMN2EPHX2 | |
| SCHEMBL441068 | 0.76 | PKM (0.37) | ENPP2KMT2AMEN1SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | MTNR1A 1862/4885MTNR1B 1684/4885TNKS 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.