Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 4/20 | 0.51 |
| ▸ | VEGFA | P15692 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637490 | 0.85 | EPAS1 (0.43) | EPAS1SCN9A | |
| SCHEMBL4637470 | 0.83 | SCN9A (0.39) | EPAS1VEGFASCN9A | |
| SCHEMBL4639089 | 0.82 | EPAS1 (0.55) | EPAS1VEGFASLC22A12PLA2G7 | |
| SCHEMBL4638321 | 0.80 | PLA2G7 (0.40) | EPAS1VEGFASCN9APLA2G7 | |
| SCHEMBL2066119 | 0.79 | PTGDR2 (0.52) | EPAS1VEGFASCN9ASLC22A12PLA2G7 | |
| SCHEMBL11121243 | 0.77 | HTR6 (0.52) | SCN9A | |
| SCHEMBL4638348 | 0.75 | EPAS1 (0.39) | EPAS1VEGFASCN9ASLC22A12 | |
| SCHEMBL14490822 | 0.74 | EPAS1 (0.44) | EPAS1VEGFASCN9ASLC22A12PLA2G7 | |
| SCHEMBL586179 | 0.74 | EPAS1 (0.44) | EPAS1VEGFASCN9ASLC22A12 | |
| SCHEMBL4194000 | 0.73 | ACLY (0.51) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | claimed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | claimed |
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |