SCHEMBL4638256

SCHEMBL4638256

C1COC(C2NCCO2)=N1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18815192 0.67
SCHEMBL6639252 0.67 ADRA2A (0.32)
SCHEMBL7624475 0.67 L3MBTL1 (0.39)
SCHEMBL20878701 0.65 MEN1 (0.38)
Hydrochloric Acid SCHEMBL4787170 0.65 L3MBTL1 (0.38)
SCHEMBL11742539 0.64 ADRA2A (0.40)
SCHEMBL19612832 0.64
SCHEMBL2778023 0.64 ADRA2A (0.38)
SCHEMBL11743173 0.64 ADRA2A (0.38)
SCHEMBL21443560 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673277-A1 [1, 2, 4]TRIAZOLO [4, 3 -B]PYRIDAZINE COMPOUNDS AS INHIBITORS OF THE C-MET TYROSINE KINASE Novartis AG (CH) 2013-12-18 EP claimed
WO-2012107500-A1 [1, 2, 4] TRIAZOLO [4, 3 -B] PYRIDAZINE COMPOUNDS AS INHIBITORS OF THE C-MET TYROSINE KINASE NOVARTIS AG (CH) 2012-08-16 WO claimed
CN-101772856-A Be used to electrode and the battery making the new composition of electrode and comprise said composition CENTRE NAT RECH SCIENT 2010-07-07 CN claimed
CN-1649830-A Substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2005-08-03 CN claimed
US-6506762-B1 Mono-, bi-, or tricyclic heterocycles may be modified to obtain potent antagonists at the NPY1 receptor. methods for the treatment of physiological disorders associated with an excess of neuropeptide Y. Novel compounds are for eating NEUROGEN CORPORATION 2003-01-14 US claimed
US-5807966-A HEATING POLYESTER, POLYAMIDE AND/OR POLYCARBONATE WITH DIPHOSPHONITE AND ANOTHER DIFUNCTIONAL ADDITIVE; CROSSLINKINGINHIBITION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US claimed
US-5760164-A STORAGE STABILITY EMS-INVENTA AG (CH) 1998-06-02 US claimed
CN-1091288-A The oxytocin antagonist OTSUKA PHARMA CO LTD (JP) 1994-08-31 CN claimed
WO-2024146880-A1 FLUORO-OXYSTEROLS POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS Institut National de la Santé et de la Recherche Médicale (FR) 2024-07-11 WO disclosed
CN-115724847-A 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives 拜耳知识产权有限责任公司 2023-03-03 CN disclosed
CN-101631464-B 2,3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives for the treatment of hyperproliferative diseases and angiogenesis-related diseases 拜耳知识产权有限责任公司 2022-12-06 CN disclosed
EP-2755976-B1 6-SUBSTITUTED 3-(QUINOLIN-6-YLTHIO)-[1,2,4]TRIAZOLO[4,3-A]PYRIDINES AS C-MET TYROSINE KINASE INHIBITORS NOVARTIS AG (CH) 2018-07-18 EP disclosed
US-20150250799-A1 Triazolopyridine Compounds NOVARTIS AG (CH) 2015-09-10 US disclosed
WO-2015024016-A2 2-PIPERIDINYL SUBSTITUTED N,3-DIHYDROXYBUTANAMIDES DUKE UNIVERSITY (US) 2015-02-19 WO disclosed
EP-0515681-A1 PEPTIDE COMPOUND FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-12-02 EP disclosed
CN-1057259-A Piperidines oxygen base and quinine epoxy group(ing) different  oxazole derivatives, their preparation and the application aspect treatment thereof SANKYO CO (JP) 1991-12-25 CN disclosed
EP-0176253-B1 PRODUCTION OF ETHYLENE OXIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-03-14 EP disclosed
EP-0330522-A2 Improved demulsified lubricating oil compositions EXXON CHEMICAL PATENTS INC. (US) 1989-08-30 EP disclosed
US-4822900-A Production of ethylene oxide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-04-18 US disclosed
EP-0176253-A1 Production of ethylene oxide IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250799-A1 Triazolopyridine Compounds FLT3, RET, MET ALDH1A1 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.