Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742539 | 0.98 | ADRA2A (0.40) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL7624475 | 0.94 | L3MBTL1 (0.39) | CHRNB2CHRNA7CHRNA4ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL4787170 | 0.93 | L3MBTL1 (0.38) | CHRNB2CHRNA7CHRNA4ADRA2AADRA2B | |
| SCHEMBL471865 | 0.71 | ADRA2A (0.44) | CYP2D6CYP1A2CYP2C9ADRA2AADRA2B | |
| SCHEMBL961726 | 0.71 | ADRA2A (0.44) | CYP2D6CYP1A2CYP2C9ADRA2AADRA2B | |
| SCHEMBL961378 | 0.70 | ADRA2A (0.47) | CYP2D6POLBCYP1A2CYP2C9ADRA2A | |
| Hydrogen Sulfide SCHEMBL721911 | 0.68 | ADRA2A (0.46) | CYP2D6CYP1A2CYP2C9ADRA2AADRA2B | |
| SCHEMBL11740603 | 0.67 | — | — | |
| SCHEMBL19612832 | 0.66 | — | — | |
| SCHEMBL11743173 | 0.66 | ADRA2A (0.38) | CYP2D6CYP1A2CYP2C9ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183179-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | CRESCENTA BIOSCIENCES (US) | 2023-06-15 | — | — | US | disclosed |
| US-10253013-B2 | Selective matrix metalloproteinase inhibitors | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253013-B2 | Selective matrix metalloproteinase inhibitors | MMP14, MMP9, MMP13 | MEN1 2616/4885CYP2D6 1769/4885CYP2C19 614/4885 |
| US-20230183179-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | FABP4, FABP1, FABP3 | MEN1 4769/4885CYP2D6 1655/4885CYP2C19 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.