Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | CAPN2 | P17655 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638369 | 0.86 | PARP1 (0.38) | CTSKPARP1CASP1CA1CA2 | |
| SCHEMBL5277557 | 0.80 | CTSK (0.41) | CTSKCTSLCTSBCTSSELANE | |
| SCHEMBL4921278 | 0.75 | TMEM97 (0.39) | CTSKCTSLCTSBPARP1CTSS | |
| SCHEMBL5242563 | 0.74 | ABCB1 (0.34) | — | |
| SCHEMBL4638299 | 0.72 | MTNR1B (0.35) | — | |
| SCHEMBL149797 | 0.69 | CASP3 (0.43) | CTSKCTSLCTSBPREPCASP1 | |
| SCHEMBL4706101 | 0.69 | ALDH1A1 (0.45) | CTSKCTSLCTSBCTSSPREP | |
| SCHEMBL5241781 | 0.69 | MTNR1B (0.36) | — | |
| SCHEMBL5277552 | 0.67 | CA1 (0.39) | CTSKCA1CA2ACHE | |
| SCHEMBL13043801 | 0.67 | CTSK (0.54) | CTSKCTSLCTSBPREPCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951712-A2 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007059952-A2 | 1-BENZAZEPINE-3-SULFONYLAMINO-2-PYRRLORIDONES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-05-31 | — | — | WO | disclosed |