Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639367 | 0.94 | TACR1 (0.32) | TACR1GPBAR1AKR1C3TP53MAPT | |
| SCHEMBL4637747 | 0.91 | EPAS1 (0.38) | TACR1GPBAR1TP53MAPTEPAS1 | |
| SCHEMBL4638040 | 0.89 | ALDH1A1 (0.31) | TACR1GPBAR1 | |
| SCHEMBL4639459 | 0.87 | TACR1 (0.34) | TACR1AKR1C3TP53MAPTEPAS1 | |
| SCHEMBL4637966 | 0.87 | KMT2A (0.41) | TACR1TP53MAPT | |
| SCHEMBL4637701 | 0.85 | GPBAR1 (0.38) | TACR1GPBAR1MAPTEPAS1 | |
| SCHEMBL4637842 | 0.85 | TACR1 (0.36) | TACR1AKR1C3TP53MAPT | |
| SCHEMBL4637940 | 0.84 | IDH1 (0.41) | TACR1GPBAR1MAPTEPAS1 | |
| SCHEMBL4637809 | 0.84 | EPAS1 (0.36) | TACR1GPBAR1MAPTEPAS1 | |
| SCHEMBL4637945 | 0.83 | EPAS1 (0.37) | TACR1GPBAR1TP53MAPTEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |