Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.71 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Phenoxyaniline SCHEMBL8976227 | 0.93 | MTNR1A (0.62) | MTNR1BMTNR1AALDH1A1LMNAMAPT | |
| SCHEMBL9162294 | 0.86 | MTNR1B (0.77) | MTNR1BMTNR1AALDH1A1LMNAMEN1 | |
| SCHEMBL3728921 | 0.85 | MTNR1A (0.62) | MTNR1BMTNR1AALDH1A1LMNAMAPT | |
| SCHEMBL12172116 | 0.84 | MTNR1B (0.73) | MTNR1BMTNR1AALDH1A1MAPTMAOB | |
| SCHEMBL3547563 | 0.84 | PKM (0.62) | MTNR1BMTNR1AALDH1A1LMNAMAPT | |
| SCHEMBL28387561 | 0.84 | PGR (0.65) | LMNAHDAC3BRAFHDAC4HDAC1 | |
| SCHEMBL4630369 | 0.83 | MTNR1B (1.00) | MTNR1BMTNR1APGR | |
| SCHEMBL171438 | 0.82 | HPGD (0.71) | MTNR1BMTNR1AALDH1A1MAPTMEN1 | |
| SCHEMBL31704006 | 0.82 | MTNR1B (0.71) | MTNR1BMTNR1AALDH1A1MAPTMEN1 | |
| SCHEMBL6516221 | 0.82 | KMT2A (0.73) | MTNR1BMTNR1AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065299-A1 | Reactive graphtic carbon nanofiber reinforced polymeric composites | LUKEHART CHARLES M (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065299-A1 | Reactive graphtic carbon nanofiber reinforced polymeric composites | GMNN, GLMN, GCN1 | MTNR1B 2287/4885MTNR1A 1121/4885ALDH1A1 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.