Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202413 | 0.77 | ALDH1A1 (0.47) | NFE2L2ALDH1A1RAB9ATRIM24TRIM33 | |
| SCHEMBL9769039 | 0.77 | NFE2L2 (0.45) | NFE2L2PKMALDH1A1GAARAB9A | |
| SCHEMBL1202412 | 0.77 | ALDH1A1 (0.47) | NFE2L2ALDH1A1RAB9ATRIM24TRIM33 | |
| 2-Chloronicotinaldehyde SCHEMBL29828177 | 0.76 | — | — | |
| 2-Chloronicotinaldehyde SCHEMBL715765 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL4048083 | 0.76 | ALDH1A1 (0.46) | NFE2L2PKMALDH1A1GAARAB9A | |
| SCHEMBL7550446 | 0.75 | LMNA (0.41) | NFE2L2ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22925143 | 0.73 | PKM (0.44) | NFE2L2PKMALDH1A1GAARAB9A | |
| SCHEMBL28618300 | 0.72 | ALDH1A1 (0.50) | ALDH1A1GAARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7551943 | 0.72 | ALDH1A1 (0.40) | NFE2L2PKMALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |