Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202412 | 0.80 | ALDH1A1 (0.47) | NFE2L2TRIM24TRIM33LMNASMN1; SMN2 | |
| SCHEMBL1202413 | 0.80 | ALDH1A1 (0.47) | NFE2L2TRIM24TRIM33LMNASMN1; SMN2 | |
| 2-Chloronicotinaldehyde SCHEMBL715765 | 0.79 | — | — | |
| 2-Chloronicotinaldehyde SCHEMBL29828177 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4048083 | 0.78 | ALDH1A1 (0.46) | NFE2L2TRIM24TRIM33LMNASMN1; SMN2 | |
| SCHEMBL25926289 | 0.78 | AMY1A (0.59) | TRIM24TRIM33AMY1ALMNASMN1; SMN2 | |
| SCHEMBL4638902 | 0.77 | NFE2L2 (0.40) | NFE2L2TRIM24TRIM33LMNASMN1; SMN2 | |
| SCHEMBL22925143 | 0.76 | PKM (0.44) | NFE2L2LMNASMN1; SMN2KMT2AKDM4E | |
| 2-Chloronicotinaldehyde SCHEMBL30893972 | 0.73 | TRIM24 (0.53) | NFE2L2TRIM24TRIM33LMNASMN1; SMN2 | |
| SCHEMBL30114987 | 0.73 | KDM4E (0.49) | LMNASMN1; SMN2KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011932-A | Anthelmintic pyridinyl acylhydrazones derivatives | UPJOHN COMPANY (US) | 1991-04-30 | — | — | US | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |