Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638841 | 0.93 | TACR1 (0.34) | KMT2AKDM4EALDH1A1TSHRTACR1 | |
| SCHEMBL4639495 | 0.89 | TACR1 (0.31) | KMT2AALDH1A1TSHRTACR1L3MBTL1 | |
| SCHEMBL4638040 | 0.88 | ALDH1A1 (0.31) | ALDH1A1TACR1L3MBTL1TDP1 | |
| SCHEMBL4638555 | 0.88 | CNR1 (0.32) | ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL4637966 | 0.88 | KMT2A (0.41) | KMT2AALDH1A1NR1H4PPARDTACR1 | |
| SCHEMBL4638545 | 0.86 | ALDH1A1 (0.38) | KMT2AKDM4EALDH1A1TSHRTACR1 | |
| SCHEMBL4639400 | 0.84 | NR1H4 (0.37) | KMT2AKDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL4637842 | 0.82 | TACR1 (0.36) | KMT2AKDM4EALDH1A1TSHRTACR1 | |
| SCHEMBL4637694 | 0.81 | EPAS1 (0.39) | KMT2AKDM4EALDH1A1TSHRTACR1 | |
| SCHEMBL4637876 | 0.81 | EPAS1 (0.39) | KMT2AKDM4EALDH1A1TSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |