Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 15/20 | 0.47 |
| ▸ | MMP1 | P03956 | 13/20 | 0.47 |
| ▸ | MMP2 | P08253 | 13/20 | 0.47 |
| ▸ | MMP13 | P45452 | 7/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MMP7 | P09237 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | MMP10 | P09238 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638907 | 0.86 | MMP1 (0.59) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL7502951 | 0.76 | ADAMTS4 (0.47) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL8000265 | 0.73 | MMP9 (0.55) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL7448192 | 0.72 | ADAMTS4 (0.43) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL8001943 | 0.70 | MMP9 (0.58) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL27547297 | 0.69 | L3MBTL1 (0.51) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL7990305 | 0.69 | MMP9 (0.62) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL8002019 | 0.69 | MMP9 (0.54) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL9938067 | 0.66 | MMP1 (0.77) | MMP9MMP1MMP2MMP13MMP3 | |
| SCHEMBL27509205 | 0.66 | MMP1 (0.66) | MMP9MMP1MMP2MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357109-B1 | Process for aryl alkyl sulfide | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | disclosed |
| EP-1357109-A2 | Process for aryl alkyl sulfide | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-29 | — | — | EP | disclosed |
| EP-0965592-A1 | Process for preparing 3-arylsulfur hydroxamic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-22 | — | — | EP | disclosed |