SCHEMBL4641272

SCHEMBL4641272

CCC(OC(=O)c1cc(Cl)c(Cl)cc1C(=O)O)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 2/20 0.36
RAB9A P51151 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
ATM Q13315 1/20 0.34
AKR1C2 P52895 2/20 0.33
AKR1C1 Q04828 2/20 0.33
SORT1 Q99523 2/20 0.33
PKM P14618 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4639933 0.92 LMNA (0.34) MEN1KMT2AALDH1A1KDM4ERAB9A
SCHEMBL4640641 0.90 HSD17B10 (0.35) MEN1KMT2ATSHRALDH1A1KDM4E
SCHEMBL4639995 0.86 ALDH1A1 (0.37) KMT2APOLBTSHRALDH1A1KDM4E
SCHEMBL4640633 0.86 ALDH1A1 (0.44) MEN1KMT2ATSHRALDH1A1KDM4E
SCHEMBL4639929 0.85 UTS2R (0.34) MEN1KMT2AKDM4ERAB9AHPGD
SCHEMBL4640681 0.85 HSD17B10 (0.40) MEN1KMT2ATSHRALDH1A1KDM4E
SCHEMBL4641141 0.84 ALDH1A1 (0.48) MEN1KMT2ATSHRALDH1A1KDM4E
SCHEMBL4640639 0.84 L3MBTL1 (0.36) MEN1KMT2AALDH1A1HPGD
SCHEMBL7199320 0.81 ALDH1A1 (0.34) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL4640058 0.81 MEN1 (0.38) MEN1KMT2APOLBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 EP disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX MEN1 3562/4885KMT2A 3313/4885POLB 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.