Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641475 | 0.99 | MAPT (0.45) | RAB9ANPC1TSHRMAPTPOLB | |
| SCHEMBL13054194 | 0.88 | HTR2C (0.56) | MAPTPOLBTHRBLMNAHTR2C | |
| SCHEMBL13054192 | 0.87 | HTR2C (0.57) | MAPTPOLBTHRBLMNAHTR2C | |
| SCHEMBL4641244 | 0.86 | ALDH1A1 (0.45) | MAPTPOLBLMNAMCHR1TMPRSS15 | |
| SCHEMBL4641303 | 0.83 | TMPRSS15 (0.44) | MAPTLMNATMPRSS15TP53KMT2A | |
| SCHEMBL4641189 | 0.83 | CHRM3 (0.41) | RAB9ANPC1MAPTPOLBTHRB | |
| SCHEMBL4647290 | 0.81 | MAPT (0.39) | RAB9ANPC1MAPTPOLBTHRB | |
| SCHEMBL4641465 | 0.80 | KMT2A (0.41) | RAB9ANPC1MAPTPOLBTHRB | |
| SCHEMBL5244723 | 0.80 | TP53 (0.56) | RAB9ANPC1TSHRMAPTPOLB | |
| SCHEMBL4641261 | 0.80 | KDM4E (0.44) | RAB9ANPC1MAPTPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |