Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641244 | 0.89 | ALDH1A1 (0.45) | TMPRSS15ALDH1A1SMN1; SMN2FAAHMAPT | |
| SCHEMBL5243702 | 0.87 | TP53 (0.50) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL4641475 | 0.83 | MAPT (0.45) | TMPRSS15MAPTLMNAKMT2ATP53 | |
| SCHEMBL4643445 | 0.83 | RAB9A (0.46) | TMPRSS15SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL5247759 | 0.81 | TP53 (0.51) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL4641355 | 0.81 | ALDH1A1 (0.44) | TMPRSS15ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL4644016 | 0.80 | ALDH1A1 (0.43) | TMPRSS15ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL4644600 | 0.80 | MAPT (0.45) | ALDH1A1SMN1; SMN2FAAHMAPTTP53 | |
| SCHEMBL4643663 | 0.79 | ALDH1A1 (0.46) | TMPRSS15ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL13054226 | 0.79 | MAPT (0.51) | ALDH1A1SMN1; SMN2MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |