Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641355 | 0.91 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TMPRSS15HTTKMT2A | |
| SCHEMBL4644016 | 0.91 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TMPRSS15HTTKMT2A | |
| SCHEMBL4643663 | 0.90 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TMPRSS15HTTKMT2A | |
| SCHEMBL4641303 | 0.89 | TMPRSS15 (0.44) | ALDH1A1SMN1; SMN2TMPRSS15HTTKMT2A | |
| SCHEMBL4641475 | 0.87 | MAPT (0.45) | TMPRSS15KMT2AMAPTTP53LMNA | |
| SCHEMBL4643445 | 0.86 | RAB9A (0.46) | SMN1; SMN2TMPRSS15KMT2AMAPTTP53 | |
| SCHEMBL4647199 | 0.86 | MCHR1 (0.46) | TMPRSS15MAPTLMNAMCHR1 | |
| SCHEMBL5247267 | 0.86 | MCHR1 (0.54) | SMN1; SMN2HTTKMT2AMAPTTP53 | |
| SCHEMBL4643026 | 0.85 | MCHR1 (0.42) | SMN1; SMN2TMPRSS15KMT2AMAPTLMNA | |
| SCHEMBL4641601 | 0.85 | MAPT (0.43) | SMN1; SMN2TMPRSS15KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |