SCHEMBL4643712

SCHEMBL4643712

CC[CH]C(=O)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
RAB9A P51151 4/20 0.34
NPC1 O15118 3/20 0.34
LMNA P02545 2/20 0.33
GLA P06280 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 3/20 0.32
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
ALDH1A1 P00352 5/20 0.32
TDP1 Q9NUW8 1/20 0.32
RECQL P46063 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
NPSR1 Q6W5P4 2/20 0.31
MAPK1 P28482 1/20 0.31
MDM2 Q00987 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644013 0.86 MAPT (0.39) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL4643573 0.80 MAPT (0.34) MAPTMEN1KMT2ALMNAMDM2
SCHEMBL4645426 0.79 MAPT (0.41) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL6555334 0.78 ZDHHC2 (0.37) MEN1KMT2AL3MBTL1TSHRCES2
SCHEMBL4641570 0.76 ALDH1A1 (0.37) MAPTLMNATSHRCES2CES1
SCHEMBL5142114 0.76 THRB (0.43) MAPTMEN1KMT2ALMNATSHR
SCHEMBL2144573 0.75 HCAR2 (0.46) MAPTKMT2ALMNAL3MBTL1TSHR
SCHEMBL2144436 0.75 HCAR2 (0.46) MAPTKMT2ALMNAL3MBTL1TSHR
SCHEMBL2144442 0.75 HCAR2 (0.46) MAPTKMT2ALMNAL3MBTL1TSHR
SCHEMBL5612980 0.73 ZDHHC2 (0.46) MAPTKMT2ARAB9AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed