SCHEMBL4642693

SCHEMBL4642693

C[CH]C(=O)Oc1ccc(Br)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
MAPT P10636 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
LDHA P00338 1/20 0.44
MGLL Q99685 1/20 0.44
MAOB P27338 4/20 0.41
MAOA P21397 2/20 0.41
NCEH1 Q6PIU2 1/20 0.41
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CHRNA7 P36544 1/20 0.39
THRB P10828 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20916986 0.83 RAB9A (0.44) LMNAMAPTRAB9AMEN1MAPK1
SCHEMBL20916987 0.83 RAB9A (0.44) LMNAMAPTRAB9AMEN1MAPK1
SCHEMBL9860556 0.82 LDHA (0.47) LMNAMAPTRAB9AMEN1MAPK1
SCHEMBL4644469 0.80 CES2 (0.52) LMNAMAPTRAB9AKMT2AMAOB
SCHEMBL4643342 0.80 ELANE (0.48) LMNAMAPTRAB9AMEN1KMT2A
SCHEMBL28744273 0.80 LDHA (0.45) LMNAMAPTRAB9AMEN1MAPK1
SCHEMBL5736870 0.79 RAB9A (0.50) LMNAMAPTRAB9AMEN1MAPK1
SCHEMBL1215248 0.78 THRB (0.55) LMNAMAPTRAB9AMEN1MAPK1
SCHEMBL4643869 0.78 MGLL (0.47) LMNAMAPTRAB9AMEN1MAPK1
SCHEMBL219758 0.77 ATM (0.47) MAPTMEN1KMT2AMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed