Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644161 | 0.84 | GABRA1 (0.78) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL27919073 | 0.83 | GABRA1 (0.56) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL11475072 | 0.81 | GABRA1 (0.54) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL2978694 | 0.79 | GABRA1 (0.52) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL7068142 | 0.78 | GABRA1 (0.50) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL22336337 | 0.78 | ALOX5 (0.41) | GABRA1GABRB1CYP3A4ALOX15ALOX12 | |
| SCHEMBL13268589 | 0.76 | GABRA1 (0.48) | GABRA1GABRB1CYP3A4TSHRALOX15 | |
| SCHEMBL5596430 | 0.76 | CYP3A4 (0.56) | GABRA1GABRB1CYP3A4TSHRTDP1 | |
| SCHEMBL16561617 | 0.76 | GABRA1 (0.41) | GABRA1GABRB1TDP1ALOX15ALDH1A1 | |
| SCHEMBL3490308 | 0.75 | AKR1C3 (0.56) | GABRA1GABRB1TSHRAKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | TYR, MMP17, MMP1 | GABRA1 4083/4885GABRB1 3312/4885CYP3A4 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.