Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644161 | 0.79 | GABRA1 (0.78) | GABRA1GABRB1TSHRTDP1CYP3A4 | |
| SCHEMBL20621495 | 0.79 | ERN1 (0.46) | GABRA1GABRB1TSHRERN1ALOX15 | |
| SCHEMBL4136739 | 0.78 | GABRA1 (0.56) | GABRA1GABRB1TSHRTDP1CYP3A4 | |
| SCHEMBL27919073 | 0.78 | GABRA1 (0.56) | GABRA1GABRB1TSHRTDP1CYP3A4 | |
| SCHEMBL7156139 | 0.77 | GABRA1 (0.36) | GABRA1GABRB1TSHRRORC | |
| SCHEMBL253259 | 0.77 | GABRA1 (0.36) | GABRA1GABRB1TSHRCYP3A4RORC | |
| SCHEMBL7066275 | 0.76 | GABRA1 (0.38) | GABRA1GABRB1TSHRTDP1CYP3A4 | |
| SCHEMBL11475072 | 0.76 | GABRA1 (0.54) | GABRA1GABRB1TSHRTDP1CYP3A4 | |
| SCHEMBL7066709 | 0.75 | MEN1 (0.43) | GABRA1GABRB1TSHRALOX15ALOX12 | |
| SCHEMBL7067636 | 0.75 | THRB (0.38) | GABRA1GABRB1TSHRALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994844-B1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING & MFG (US) | 2002-07-31 | — | — | EP | claimed |
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0980532-B1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING & MFG (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6533959-B2 | Formed from monomers such as 2-(4,6-dibromo-2-isopropyl phenoxy)ethyl acrylate; high index of refraction, useful to control flow and intensity of light | 3M INNOVATIVE PROPERTIES COMPANY | 2003-03-18 | — | — | US | disclosed |
| EP-0980398-B1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING & MFG (US) | 2002-11-27 | — | — | EP | disclosed |
| US-20020123590-A1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-05 | — | — | US | disclosed |
| EP-0994844-B1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING & MFG (US) | 2002-07-31 | — | — | EP | disclosed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-6355754-B1 | 4,6-DIBROMO-2-ALKYL PHENYL ACRYLATE AND AROMATIC (METH)ACRYLATE COMONOMERS; OPTICS, LOW MELTING | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-12 | — | — | US | disclosed |
| US-6261700-B1 | HARD COATING | 3M INNOVATIVE PROPERTIES COMPANY | 2001-07-17 | — | — | US | disclosed |
| EP-1105430-A1 | CERAMER CONTAINING A BROMINATED POLYMER AND INORGANIC OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0994844-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |
| EP-0980398-A1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0980532-A1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-2000006622-A1 | CERAMER CONTAINING A BROMINATED POLYMER AND INORGANIC OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| US-5932626-A | BRIGHTNESS PROMOTING FILM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1998050340-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998050805-A1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998050442-A1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123590-A1 | Brominated materials | PBRM1, TUBB3, TUBB | GABRA1 906/4885GABRB1 837/4885TSHR 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.