SCHEMBL4645339

SCHEMBL4645339

[CH2]CCCC(=O)O[Si](C)(C)CCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.36
TSHR P16473 4/20 0.35
LMNA P02545 3/20 0.34
PAM P19021 2/20 0.33
EPHX2 P34913 1/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ALDH1A1 P00352 2/20 0.31
DNM1 Q05193 1/20 0.31
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
NAAA Q02083 1/20 0.31
CYP3A4 P08684 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644437 0.91 DGKA (0.33) DGKATSHRLMNAPAMEPHX2
SCHEMBL14735468 0.89 CES1 (0.41) DGKATSHRLMNAPAMEPHX2
SCHEMBL6546145 0.89 TSHR (0.44) DGKATSHRLMNAPAMEPHX2
SCHEMBL6545806 0.87 TSHR (0.39) DGKATSHRLMNAPAMCES2
SCHEMBL28423837 0.85 DGKA (0.52) DGKATSHRLMNAPAMMAPT
SCHEMBL2599070 0.85 ALDH1A1 (0.44) DGKATSHRLMNAPAMEPHX2
SCHEMBL4644370 0.84 DGKA (0.37) DGKATSHRLMNAPAMMAPT
SCHEMBL4642209 0.84 DGKA (0.37) DGKATSHRLMNAPAMMAPT
SCHEMBL4647504 0.83 TSHR (0.38) DGKATSHRLMNAALDH1A1
SCHEMBL4642164 0.83 NAAA (0.31) DGKATSHRCES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed