SCHEMBL4644437

SCHEMBL4644437

[CH2]CCC(=O)O[Si](C)(C)CCCC

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.33
TSHR P16473 2/20 0.33
CES2 O00748 5/20 0.32
CES1 P23141 5/20 0.32
CA12 O43570 2/20 0.32
CA14 Q9ULX7 2/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 2/20 0.31
PAM P19021 2/20 0.31
EPHX2 P34913 1/20 0.30
AKR1B1 P15121 1/20 0.30
TP53 P04637 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645339 0.91 DGKA (0.36) DGKATSHRCES2CES1CA12
SCHEMBL6545806 0.88 TSHR (0.39) DGKATSHRCES2CES1CA12
SCHEMBL6546145 0.86 TSHR (0.44) DGKATSHRCES2CES1CA12
SCHEMBL14735468 0.86 CES1 (0.41) DGKATSHRCES2CES1LMNA
SCHEMBL2599070 0.86 ALDH1A1 (0.44) DGKATSHRCES2CES1CA12
SCHEMBL4642164 0.85 NAAA (0.31) DGKATSHRCES2CES1CA12
SCHEMBL4643731 0.83 CA12 (0.36) DGKATSHRCES2CES1CA12
SCHEMBL4643559 0.83 NAAA (0.39) DGKATSHRCES2CES1CA12
SCHEMBL28423837 0.83 DGKA (0.52) DGKATSHRCES2CES1LMNA
SCHEMBL6658596 0.81 AKR1B1 (0.43) TSHRALDH1A1PAMAKR1B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed