SCHEMBL4645405

SCHEMBL4645405

c1cc(Cc2ccc(CSCC3CS3)cc2)ccc1CSCC1CS1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.31
ALDH1A1 P00352 3/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1402882 0.94 CRBN (0.33) CRBNALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL4646933 0.88 BCHE (0.34) CRBNALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL4648441 0.85 CRBN (0.33) CRBN
SCHEMBL14209991 0.84 CRBN (0.44) CRBNALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL2769336 0.82 KMT2A (0.34) KMT2A
SCHEMBL4645049 0.80 MMP2 (0.38) ALDH1A1
SCHEMBL1402639 0.78 SLC11A2 (0.36) CRBNALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL1402696 0.76 LTA4H (0.37) ALDH1A1ESR1ESR2CYP3A4TSHR
SCHEMBL1402519 0.73 CYP1A2 (0.36) CYP3A4
SCHEMBL6601719 0.72 CRBN (0.30) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080206668-A1 NEGATIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
EP-1962139-A1 Negative resist composition and pattern forming method using the same FUJIFILM Corporation (JP) 2008-08-27 EP disclosed