Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485599 | 0.84 | WDR5 (0.68) | POLBWDR5LDHANCEH1MAOB | |
| SCHEMBL2016154 | 0.81 | POLB (0.52) | POLBWDR5LDHANCEH1MAOB | |
| SCHEMBL607844 | 0.81 | POLB (0.52) | POLBWDR5LDHANCEH1MAOB | |
| SCHEMBL31520424 | 0.81 | POLB (0.52) | POLBWDR5LDHANCEH1MAOB | |
| SCHEMBL2262992 | 0.80 | WDR5 (0.68) | WDR5LDHAMMP3HDAC8NR4A1 | |
| SCHEMBL3922382 | 0.78 | LDHA (0.69) | WDR5LDHANPC1MAPTRAB9A | |
| SCHEMBL29819980 | 0.78 | WDR5 (0.50) | WDR5LDHAMMP3HDAC8NR4A1 | |
| SCHEMBL608187 | 0.78 | WDR5 (0.50) | WDR5LDHAMMP3HDAC8NR4A1 | |
| SCHEMBL8681030 | 0.78 | CYP2A6 (0.52) | POLBWDR5LDHANCEH1NR4A1 | |
| SCHEMBL8681263 | 0.77 | CYP1A1 (0.55) | POLBWDR5LDHANCEH1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107935936-A | Benzimidazole compound and derivative, Organic Electron Transport Material and its preparation and application | 华南理工大学 | 2018-04-20 | — | — | CN | claimed |
| CN-106518708-B | The synthesis and application of new FXR activators | 中国药科大学 | 2018-02-16 | — | — | CN | claimed |
| US-11678576-B2 | Heterocyclic compound and organic light emitting element comprising same | LT MATERIALS CO., LTD. (KR) | 2023-06-13 | — | — | US | disclosed |
| US-11678576-B2 | Heterocyclic compound and organic light emitting element comprising same | LT MATERIALS CO., LTD. (KR) | 2023-06-13 | — | — | US | disclosed |
| CN-110698501-B | Transition metal complex and application thereof | 广州华睿光电材料有限公司 | 2022-10-04 | — | — | CN | disclosed |
| EP-3858831-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LT Materials Co., Ltd. (KR) | 2021-08-04 | — | — | EP | disclosed |
| US-20210202863-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LT MATERIALS CO., LTD. (KR) | 2021-07-01 | — | — | US | disclosed |
| CN-107879968-B | Luminescent material containing polar substituent group naphthoindene carbazole unit and preparation and application thereof | 华南协同创新研究院 | 2021-03-16 | — | — | CN | disclosed |
| CN-106675551-B | Bipolar small-molecule luminescent material which can be processed by environment-friendly solvent and takes naphthoindene fluorene unit as core, and preparation method and application thereof | 华南理工大学 | 2020-04-28 | — | — | CN | disclosed |
| WO-2020067594-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | 희성소재(주) | 2020-04-02 | — | — | WO | disclosed |
| CN-110698501-A | Transition metal complex and application thereof | 广州华睿光电材料有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-107935936-A | Benzimidazole compound and derivative, Organic Electron Transport Material and its preparation and application | 华南理工大学 | 2018-04-20 | — | — | CN | disclosed |
| CN-106518708-B | The synthesis and application of new FXR activators | 中国药科大学 | 2018-02-16 | — | — | CN | disclosed |
| CN-106675551-A | Bipolar small molecular luminescent material capable of being processed by adopting environment-friendly solvent and taking naphtho-indenofluorene unit as core as well as production method and application of bipolar small molecular luminescent material | 华南理工大学 | 2017-05-17 | — | — | CN | disclosed |
| CN-106518708-A | Synthesis and applications of novel FXR agonists | 中国药科大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-106187908-A | One class can use small molecule emitter material containing naphtho-indenes fluorenes unit that environmentally friendly solvent processes and preparation method and application | 华南理工大学 | 2016-12-07 | — | — | CN | disclosed |
| EP-1675830-A4 | HETEROCYCLIC AMIDES AND SULFONAMIDES | SCIOS INC (US) | 2008-08-20 | — | — | EP | disclosed |
| US-20060199821-A1 | Heterocyclic amides and sulfonamides | SCIOS, INC. (US) | 2006-09-07 | — | — | US | disclosed |
| EP-1675830-A2 | HETEROCYCLIC AMIDES AND SULFONAMIDES | SCIOS INC. (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005033072-A2 | HETEROCYCLIC AMIDES AND SULFONAMIDES | SCIOS INC. (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210202863-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | CRY1, CRY2, CYP1A1 | POLB 3354/4885WDR5 2656/4885LDHA 1247/4885 |
| US-20060199821-A1 | Heterocyclic amides and sulfonamides | MAP4K2, MAP3K8, MAP3K2 | POLB 4065/4885WDR5 2804/4885LDHA 4138/4885 |
| US-11678576-B2 | Heterocyclic compound and organic light emitting element comprising same | CRY1, CRY2, CYP1A1 | POLB 3354/4885WDR5 2656/4885LDHA 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.