Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643026 | 0.91 | MCHR1 (0.42) | MCHR1MAPTLMNATMPRSS15 | |
| SCHEMBL4641601 | 0.91 | MAPT (0.43) | MCHR1MAPTLMNATMPRSS15 | |
| SCHEMBL4643038 | 0.90 | MCHR1 (0.48) | MCHR1MAPTTMPRSS15 | |
| SCHEMBL4644016 | 0.89 | ALDH1A1 (0.43) | MCHR1MAPTLMNATMPRSS15 | |
| SCHEMBL4645813 | 0.87 | TMPRSS15 (0.41) | MCHR1MAPTLMNATMPRSS15 | |
| SCHEMBL13054261 | 0.87 | MCHR1 (0.59) | MCHR1MAPTLMNA | |
| SCHEMBL4641244 | 0.86 | ALDH1A1 (0.45) | MCHR1MAPTLMNATMPRSS15 | |
| SCHEMBL4641593 | 0.86 | MAPT (0.46) | MCHR1MAPTLMNATMPRSS15 | |
| SCHEMBL4643578 | 0.85 | MCHR1 (0.44) | MCHR1MAPTTMPRSS15 | |
| SCHEMBL4641355 | 0.85 | ALDH1A1 (0.44) | MAPTLMNATMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |