Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646920 | 0.83 | CCR1 (0.41) | KMT2AHTTKDM4EALDH1A1POLB | |
| SCHEMBL4648354 | 0.82 | POLB (0.43) | LSSKMT2AKDM4EALDH1A1POLB | |
| SCHEMBL3379302 | 0.81 | CXCR4 (0.42) | KDM4EALDH1A1POLB | |
| SCHEMBL4648112 | 0.78 | SCN1A (0.39) | KMT2AKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL4643540 | 0.77 | POLB (0.38) | KMT2AKDM4EALDH1A1POLBP2RX7 | |
| SCHEMBL4647711 | 0.76 | HRH3 (0.45) | POLBP2RX7 | |
| SCHEMBL4648462 | 0.76 | HTR7 (0.41) | LSSKMT2AALDH1A1POLBMEN1 | |
| SCHEMBL3376162 | 0.75 | ALDH1A1 (0.49) | KMT2AKDM4EALDH1A1POLBP2RX7 | |
| SCHEMBL3377597 | 0.75 | ALDH1A1 (0.49) | KMT2AKDM4EALDH1A1POLBP2RX7 | |
| SCHEMBL3377318 | 0.75 | PKM (0.49) | KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | Pfizer Products Incorporated (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006136924-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-12-28 | — | — | WO | disclosed |