Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647260 | 0.86 | BCHE (0.39) | KMT2AMEN1MAPTL3MBTL1IDO1 | |
| SCHEMBL4647900 | 0.86 | EPHX1 (0.35) | MAPTGRIN1GRIN2BIDO1CYP1A2 | |
| SCHEMBL4647489 | 0.86 | CYP2D6 (0.39) | KMT2AMEN1MAPTIDO1NPSR1 | |
| SCHEMBL4646889 | 0.82 | CYP1A2 (0.42) | KMT2AMEN1MAPTMAPK1IDO1 | |
| SCHEMBL4647948 | 0.81 | L3MBTL1 (0.46) | KMT2AMEN1MAPTL3MBTL1TDP1 | |
| SCHEMBL4648577 | 0.81 | BCHE (0.36) | KMT2AMEN1MAPTL3MBTL1HPGD | |
| SCHEMBL4645997 | 0.78 | MAPT (0.50) | KMT2AMEN1MAPTL3MBTL1TDP1 | |
| SCHEMBL4645225 | 0.78 | NOS3 (0.37) | MAPTGRIN1GRIN2BIDO1HPGD | |
| SCHEMBL4646000 | 0.75 | ALDH1A1 (0.54) | KMT2AMEN1MAPTTDP1NPSR1 | |
| SCHEMBL4645410 | 0.75 | CRHBP (0.35) | IDO1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |