Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645410 | 0.87 | CRHBP (0.35) | IDO1CRHBPCRHR2CYP1A2CYP3A4 | |
| SCHEMBL4647590 | 0.86 | ACHE (0.39) | IDO1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL4647489 | 0.86 | CYP2D6 (0.39) | IDO1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4646174 | 0.86 | KMT2A (0.39) | IDO1CTSBGRIN1GRIN2BCYP1A2 | |
| SCHEMBL4648577 | 0.81 | BCHE (0.36) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL4645225 | 0.78 | NOS3 (0.37) | IDO1GRIN1GRIN2BCYP2D6GAA | |
| SCHEMBL4648033 | 0.75 | ALDH1A1 (0.41) | GAALMNAMAPTRAB9ASLC22A2 | |
| SCHEMBL4647260 | 0.73 | BCHE (0.39) | IDO1POLBGAALMNAMAPT | |
| SCHEMBL4646889 | 0.71 | CYP1A2 (0.42) | EPHX1IDO1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4646608 | 0.71 | ACHE (0.41) | IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |