Sugi Predict

Sugi Predict / Compounds / SCHEMBL4648803

SCHEMBL4648803

SCHEMBL4648803

CC(C)(C)OC(=O)NCCNC(=O)CBr

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.53
▸ MEN1 O00255 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ EPHX1 P07099 1/20 0.47
▸ MAOA P21397 1/20 0.46
▸ MAOB P27338 1/20 0.46
▸ CA1 P00915 7/20 0.44
▸ CA2 P00918 7/20 0.44
▸ CA12 O43570 4/20 0.44
▸ CA9 Q16790 4/20 0.44
▸ MALT1 Q9UDY8 1/20 0.41
▸ HTT P42858 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ BCHE P06276 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ GFER P55789 1/20 0.39
▸ IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7242095 0.93 TDP1 (0.59) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL19611966 0.93 TDP1 (0.64) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL3871437 0.91 TDP1 (0.67) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL14536293 0.91 TDP1 (0.67) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL26966754 0.88 TDP1 (0.46) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL12013554 0.88 TDP1 (0.46) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL10067925 0.88 TDP1 (0.46) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL22602535 0.87 TDP1 (0.53) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL3341020 0.85 TDP1 (0.67) TDP1MEN1GAAKMT2AEPHX1
SCHEMBL22602576 0.85 TDP1 (0.51) TDP1MEN1GAAKMT2AEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391981-B2 Chromogenic peroxidase substrates AGILENT TECHNOLOGIES, INC. (US) 2025-08-19 — — US disclosed
US-20250073338-A1 CONJUGATE COMPOUNDS AND COMPOSITIONS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2025-03-06 — — US disclosed
US-20240360495-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2024-10-31 — — US disclosed
WO-2024220546-A2 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES AND METHODS OF USE AND SYNTHETIC PROCESSES AND INTERMEDIATES PEAK BIO, INC. (US) 2024-10-24 — — WO disclosed
US-11993810-B2 Chromogenic peroxidase substrates AGILENT TECHNOLOGIES, INC. (US) 2024-05-28 — — US disclosed
EP-4336184-A2 CHROMOGENIC PEROXIDASE SUBSTRATES Agilent Technologies, Inc. (A Delaware Corporation) (US) 2024-03-13 — — EP disclosed
EP-3391056-B1 CHROMOGENIC PEROXIDASE SUBSTRATES AGILENT TECHNOLOGIES INC (US) 2024-01-17 — — EP disclosed
EP-3391056-B1 CHROMOGENIC PEROXIDASE SUBSTRATES AGILENT TECHNOLOGIES INC (US) 2024-01-17 — — EP disclosed
US-20230190943-A1 ALGINIC ACID DERIVATIVE BONDED TO NONSTEROIDAL ANTI-INFLAMMATORY COMPOUND MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2023-06-22 — — US disclosed
US-20230002816-A1 CHROMOGENIC PEROXIDASE SUBSTRATES DAKO DENMARK APS (DK) 2023-01-05 — — US disclosed
US-20030077635-A1 Dendrimers and methods for their preparation and use DAKO A/S 2003-04-24 — — US disclosed
US-20020173049-A1 Controlling protein levels in eucaryotic organisms PROTEINIX, INC. 2002-11-21 — — US disclosed
US-20020146843-A1 Controlling protein levels in eucaryotic organisms PROTEINIX, INC. 2002-10-10 — — US disclosed
EP-1192465-A1 DETECTION USING DENDRIMERS BEARING LABELS AND PROBES DAKO A/S (DK) 2002-04-03 — — EP disclosed
EP-1156817-A1 CONTROLLING PROTEIN LEVELS IN EUCARYOTIC ORGANISMS Proteinix, Inc. (US) 2001-11-28 — — EP disclosed
US-6306663-B1 GENERATING A MOULATOR FOR ACTIVATING UBIQUITINATION OF TARGET PROTEIN; FOR USE IN THE TREATMENT OF INFECTIONS, INFLAMMATION, CANCER AND GENETIC DISORDERS; FOR USE AS INSECTICIDES AND HERBICIDES PROTEINEX, INC. 2001-10-23 — — US disclosed
WO-2001002861-A1 DETECTION USING DENDRIMERS BEARING LABELS AND PROBES DAKO A/S (DK) 2001-01-11 — — WO disclosed
WO-2000047220-A1 CONTROLLING PROTEIN LEVELS IN EUCARYOTIC ORGANISMS PROTEINIX, INC. (US) 2000-08-17 — — WO disclosed
WO-1999000669-A1 NUCLEOBASE HETEROCYCLIC COMBINATORIALIZATION ISIS PHARMACEUTICALS, INC. (US) 1999-01-07 — — WO disclosed
US-4515920-A Synthesis of peptides and proteins THE ROCKEFELLER UNIVERSITY (US) 1985-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360495-A1 CHROMOGENIC PEROXIDASE SUBSTRATES MPO, TPO, TYR TDP1 1730/4885MEN1 3504/4885GAA 114/4885
US-11993810-B2 Chromogenic peroxidase substrates MPO, TPO, TYR TDP1 1730/4885MEN1 3504/4885GAA 114/4885
US-20230002816-A1 CHROMOGENIC PEROXIDASE SUBSTRATES MPO, TPO, TYR TDP1 1730/4885MEN1 3504/4885GAA 114/4885
US-20250073338-A1 CONJUGATE COMPOUNDS AND COMPOSITIONS GPR119, GPR65, GPR55 TDP1 4707/4885MEN1 1885/4885GAA 2245/4885
US-20230190943-A1 ALGINIC ACID DERIVATIVE BONDED TO NONSTEROIDAL ANTI-INFLAMMATORY COMPOUND ALG1, ALG8, ALG3 TDP1 2939/4885MEN1 3649/4885GAA 153/4885
US-12391981-B2 Chromogenic peroxidase substrates MPO, TPO, TYR TDP1 1730/4885MEN1 3504/4885GAA 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.