Sugi Predict

Sugi Predict / Compounds / SCHEMBL4649487

SCHEMBL4649487

SCHEMBL4649487

COc1ccc2c(=O)cc(-c3ccccc3)oc2c1OC

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 0.76
▸ CYP2C19 P33261 4/20 0.76
▸ CYP1A2 P05177 3/20 0.76
▸ NCOA1 Q15788 1/20 0.76
▸ NCOA3 Q9Y6Q9 1/20 0.76
▸ ALDH1A1 P00352 4/20 0.74
▸ CYP2C9 P11712 3/20 0.74
▸ HPGD P15428 3/20 0.74
▸ MAPT P10636 3/20 0.74
▸ TERT O14746 4/20 0.69
▸ CYP1A1 P04798 4/20 0.66
▸ CYP1B1 Q16678 3/20 0.66
▸ ACHE P22303 1/20 0.63
▸ PLK1 P53350 1/20 0.63
▸ BACE1 P56817 1/20 0.63
▸ KDM4E B2RXH2 3/20 0.60
▸ HSD17B10 Q99714 2/20 0.60
▸ TUBB4A P04350 1/20 0.59
▸ TUBB P07437 1/20 0.59
▸ TUBA3C P0DPH7 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6612282 0.88 TUBB4A (0.76) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL21647169 0.86 CYP1A2 (0.73) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL27381836 0.86 CYP1A2 (0.73) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL14286203 0.86 CYP1A2 (1.00) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL16704751 0.86 CYP1A1 (0.76) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL29612043 0.86 TERT (0.77) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL988001 0.86 TERT (0.77) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL6617350 0.86 TERT (0.65) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL19097304 0.85 ALDH1A1 (0.68) CYP3A4CYP2C19CYP1A2NCOA1NCOA3
SCHEMBL6616218 0.85 CYP3A4 (0.73) CYP3A4CYP2C19CYP1A2NCOA1NCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 — — CN claimed
WO-2025038960-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO claimed
WO-2025038963-A1 OLIGONUCLEOTIDES CONTAINING MULTIPLE LIGANDS AND/OR LIPIDS ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO claimed
WO-2025038970-A1 MODIFIED OLIGONUCLEOTIDES CONTAINING MULTIPLE OLIGONUCLEOTIDES ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO claimed
WO-2025038971-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT A NUCLEOBASE, 2' POSITION, OR 3' POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO claimed
CN-116426495-A flavone-O-methyltransferase and application thereof in synthesis of iso-wogonin and mosla flavone 中国科学院天津工业生物技术研究所 2023-07-14 — — CN claimed
CN-113373125-A flavone-O-methyltransferase and its application in synthesis of wogonin, isowogonin and thuja flavone 中国科学院天津工业生物技术研究所 2021-09-10 — — CN claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 — — US claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 — — CN disclosed
CN-121577766-A Method, system and application for detecting adulteration in vegetable oil 长沙市食品药品检验所 2026-02-27 — — CN disclosed
WO-2025038963-A1 OLIGONUCLEOTIDES CONTAINING MULTIPLE LIGANDS AND/OR LIPIDS ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO disclosed
EP-1373244-A2 SUBSTITUTED BENZOPYRANONES AS TELOMERASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-02 — — EP disclosed
WO-2003057210-A1 COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-07-17 — — WO disclosed
US-20030125264-A1 Methods For Treating Wounds KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-03 — — US disclosed
US-20020160983-A1 Substituted benzopyranones as telomerase inhibitors PHARMACIA ITALIA S.P.A. (IT) 2002-10-31 — — US disclosed
WO-2002074036-A2 SUBSTITUTED BENZOPYRANONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-09-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020160983-A1 Substituted benzopyranones as telomerase inhibitors TERT, TERF2, TERF2IP CYP3A4 3385/4885CYP2C19 3703/4885CYP1A2 3159/4885
US-20030125264-A1 Methods For Treating Wounds FGF2, MMP1, FIBP CYP3A4 3010/4885CYP2C19 2389/4885CYP1A2 1713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.