Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702712 | 0.88 | LMNA (0.44) | LMNAMAPK1SMN1; SMN2TDP1MASP2 | |
| SCHEMBL9575552 | 0.88 | PTPN1 (0.39) | LMNAMAPK1SMN1; SMN2TDP1MASP2 | |
| SCHEMBL3844085 | 0.84 | KMT2A (0.42) | LMNAMAPK1SMN1; SMN2TDP1MAPT | |
| SCHEMBL9575509 | 0.83 | MASP2 (0.41) | LMNAMAPK1SMN1; SMN2TDP1MASP2 | |
| SCHEMBL30062473 | 0.79 | ALPL (0.48) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5148413 | 0.79 | ALPL (0.48) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8241642 | 0.79 | ALDH1A1 (0.54) | LMNAMAPK1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7519257 | 0.78 | CYP1A2 (0.51) | LMNAMAPK1SMN1; SMN2TDP1MAPT | |
| SCHEMBL3840693 | 0.77 | LMNA (0.43) | LMNAMAPK1MAPTPTPN1KMT2A | |
| Hydrazine SCHEMBL11393765 | 0.77 | MEN1 (0.47) | LMNATDP1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278414-B1 | PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | claimed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | claimed |
| EP-1245635-B1 | FLUOROELASTOMER COMPOSITION FOR CROSSLINKING | DAIKIN IND LTD (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-6878778-B1 | Fluoroelastomer composition for crosslinking | DAIKIN INDUSTRIES, LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| EP-1245635-A1 | FLUOROELASTOMER COMPOSITION FOR CROSSLINKING | Daikin Industries, Ltd. (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0278414-B1 | PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5028728-A | Process for the preparation of reaction products of 2,2-bis-(4-hydroxphenyl)-hexafluoropropane and new derivatives of this type | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |